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The reported adverse reactions following parenteral administration of vitamin B12 include: Generalized : Anaphylaxis and death Cardiovascular : Pulmonary edema and congestive cardiac/heart failure during early treatment

International Journal of Obesity .Read source (2001)

B12 plays many important roles in the human body, including: Nerve function Brain health Red blood cell production DNA synthesis Energy production Some people simply do not get enough Vitamin B12 in their diet to meet the bodys demands, while others have difficulty absorbing it

Link Vijay-Kumar, M., et al

Certain factors may put you at increased risk for B12 deficiencyincluding a vegetarian or vegan diet, specific medical conditions (such as Crohns or celiac disease, or a history of gastric surgery), and age over 50