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Effectively, the GSDMD-mediated pyroptosis process promotes the release of mtDNA

Targeting the microbiome to improve human health with the approach of personalized medicine: latest aspects and current updates

Supplementary Table 12 (download XLSX The potencies of peptides designed in this study by the multi-task neural-network ensemble model against human GCGR were measured in triplicate, in three independent measurements

On the other hand, dose-response relationships for these peptides are often biphasic or bell-shaped, meaning that more is not better and that higher concentrations can lose the effect or even reverse it

Ferritin light chain (FTL) was significantly elevated and colocalized with 4-HNE signals in infected hamster lungs compared with mock-infected group, which is consistent with analysis on human lung samples (Fig