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PLoS ONE 10:e0124844 Acknowledgements Open access funding provided by Projekt DEAL

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Histological Findings in Mice Brain in Cerebral cortex, Hippocampus and Corpus Callosum of Mice Brain Figure 3 shows H&E-stained sections of cerebral cortex (CTX) and hippocampus (HC)

Thus, it is possible that our monthly APAP dosage of 300 mg/Kg, which appears to occur in an acute manner, did not result in hyperammonemia and or disruption of vascular integrity at the designated administration time points