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Specifically, the IDF posits that MetS is a cluster of the most dangerous heart attack risk factors: diabetes and raised fasting plasma glucose, abdominal obesity, high cholesterol, and high blood pressure. According to data from the World Health Organization (2016), the leading cause of death worldwide was ischemic heart disease, followed by stroke and chronic obstructive pulmonary disease (198) all of which are related to MetS

(Please note that I am presenting a tremendous over-simplification about genetics here

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Thuwanut P, Chatdarong K, Johannisson A, Bergqvist AS, Sderquist L, Axnr E (2010) Cryopreservation of epididymal cat spermatozoa: effects of in vitro antioxidative enzymes supplementation and lipid peroxidation induction