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[7] Additionally, without gluconeogenesis, pyruvate would be lost, reducing the bodys capacity to produce ATP via aerobic respiration (more than 10 ATP molecules per pyruvate oxidized), making its conservation essential during energy stress

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Proc Natl Acad Sci USA 93 : 83188323 Werner H, Le Roith D (2000) New concepts in regulation and function of the insulin-like growth factors: implications for understanding normal growth and neoplasia

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