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It should be understood that the following drawings only show some embodiments of the present invention, and thus It should be regarded as a limitation on the scope, and those skilled in the art can also obtain other related drawings based on these drawings without creative work

Propranolol is one of the most common and effective drug of choice for CVS

Notably, most of these natural products have undergone extensive study and validation as drugs 56 or food additives 57 , endowing them with heightened clinical translational value owing to their established safety profiles and druggability, in contrast to unexplored chemical structures

In the process of tumor treatment, inhibition of GPX4 is not always effective, and sometimes drugs resistances occur

However, this study was prematurely terminated owing to a change in the drug sponsor (NCT01920477)