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Mazza, G., Fukumoto, L., Delaquis, P., Girard, B

Randomized trials of dopamine agonists in restless legs syndrome: a systematic review, quality assessment, and meta-analysis

Ann Rheum Dis (2023) 82:3516

Selective GH Release No ACTH or Cortisol Effect Unlike GHRP-6 and GHRP-2, which both resulted in elevated plasma ACTH and cortisol levels in swine models, Ipamorelin did not release ACTH or cortisol at levels significantly different from GHRH stimulation alone even at doses more than 200-fold higher than the ED50 for GH release