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Acetylation modifications of the expression of the DNA damage-related gene MCM4 Minichromosome Maintenance 4 (MCM4) is a protein that plays a crucial role in DNA replication, primarily ensuring the accurate duplication of DNA and the proper progression of the cell cycle

Akt is a critical kinase downstream of IGF-I action and most of IGF-Is anabolic and anti-apoptotic effects are mediated by phosphorylation and activation of Akt

Notably, human genome-wide association study (GWAS) data have shown that single-nucleotide polymorphisms in the vicinity of the TGFBI gene are associated with type 1 diabetes risk, and TGFBI has been shown to promote islet survival, function and regeneration in mice [43]

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However, the percentage of atypical sperm forms showed a significantly negative relationship to seminal GSSG