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Methionine in turn is required for the synthesis of S-adenosylmethionine, a methyl group donor used in many biological methylation reactions, including the methylation of a number of sites within DNA, RNA, and proteins ( Figure 1 ) (3)

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Abbreviations COVID-19: Novel coronavirus disease 2019 IL-6: Interleukin-6 G-CSF: Granulocyte colony-stimulating factor TNF-: Tumor necrosis factor- MSCs: Mesenchymal stem cells hWJCs: Human umbilical cord Whartons jelly-derived mesenchymal stem cells GVHD: Graft-versus-host disease CRP: C-reactive protein RT-PCR: Real-time polymerase chain reaction CT: Computerized tomography GGO: Ground-glass opacity FBS: Fetal bovine serum RCD: Regulated cell death References Zu ZY, Jiang MD, Xu PP, Chen W, Ni QQ, Lu GM, et al