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Additionally, we reviewed relevant research on the modulation of ferroptosis signaling pathways as a potential approach for developing antidepressant interventions

In macrophages, HO-1 mediates both classical ferroptosis pathways via glutathione peroxidase 4 (GPX4) regulation and non-classical, erythrophagocytosis-induced ferroptosis, contributing to plaque instability

Brio et al

GSTU20 has been assayed for activity toward model xenobiotic substrate CDNB and BITC which are the typical GST substrates, revealing high GSH-conjugating activity ( in vitro due to the rare abundance