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The BcL-2 gene family promotes the release of cytochrome C from the mitochondrial membrane and its binding with apoptosis protease activating factor 1 (Apaf-1) to regulate mitochondrial membrane permeability (Zuo et al., 2019)

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As with all research compounds, investigators should implement appropriate laboratory safety protocols and follow institutional guidelines for handling investigational chemical compounds in controlled research environments

The label recommends funduscopic examination at the start of therapy and periodically

International classification of rodent tumours