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Concurrently, elevated levels of triglycerides, FAs, and fatty acid ethyl esters were detected in pancreatic tissue, indicating active involvement of LDs in pathological lipid metabolism (64)

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For example, in human PAECs under hypoxic conditions, the levels of ROS were increased, while the levels of mitochondrial thioredoxin 2, an antioxidant protein, were reduced which could contribute to exacerbating hypoxia-induced ROS production [157]

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