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MedComm 5(3):e497 Karunarathna I et al (2024) Glutathione for skin lightening: a review of efficacy, safety, and clinical evidence

This process employs hard milling media within rotating or vibrating mills, where repeated high-energy impacts induce deformation and fracture, leading to nanoscale material refinement

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Real-world patients may be older, present with multiple comorbidities, receive concomitant medications, and face challenges related to healthcare access, adherence, and long-term disease management

In AD, NF-B activation is linked to -amyloid plaque-induced microglial stimulation [445], while in PD, -synuclein aggregates act as DAMPs that activate TLR2 [446]