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doi: 10.1155/2013/964539

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In chronic obstructive pulmonary disease, a disease with increased prevalence in aged individuals, zinc deficiency hinders the clearance of apoptotic epithelial cells by alveolar macrophages, contributing to persistent inflammation [234]

Additionally, DFO mitigates iron overload and ferroptosis in cortical motor neurons after SCI, aiding in motor recovery (241)

This selectivity is the compounds primary research utility: it allows investigators to study IRR-mediated signaling in isolation, without the confounding receptor crosstalk associated with full-length erythropoietin in cell-based assay systems