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Conversely, biomarkers with slow transport kinetics are more accurately quantified through direct blood analysis

In the present study, we found the augment of hepatocyte oxidation and premature aging, along with the decrease of plasm IGF-1 level in patients with liver fibrosis and CCl 4 -induced liver injury rat models

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The M105I mutation alters the preferential plasma membrane-bound distribution of -SNAP in vivo To explore whether the reduction in protein-lipid interaction of the -SNAP M105I mutant, as suggested by in silico studies and observed in in vitro experiments, was also present in vivo, we analyzed the subcellular distribution of -SNAP in the brain of WT and hyh mutant mice