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Name: l-carnitine supplementation pubmed for the Management of Fatigue in Patients With Cancer: An Eastern Cooperative Oncology Group Phase III, Randomized, Double-Blind, Placebo-Controlled Trial Changes in carnitine profiles during
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doi: 10.1089/ars.2011.4198

In 1974, permission to conduct clinical trials (Investigational New Drug Application (IND) from the Food and Drug Administration) was issued (Goldstein and Badamchian 2004)