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We generated renal TEC-specific PRMT1 KO mice (PT-Prmt1/, CKO) to investigate the role of PRMT1 in lipid metabolism regulation and conducted proteomic sequencing on samples from the Gly and Gly-CKO groups

doi: 10.1016/j.micpath.2013.12.005 265 WangX-YWangR-CQuZ-YZhuY-ZLiY-L

Data extraction and study outcomes Four reliable authors/reviewers performed the data extraction in a well-defined excel sheet, the excel sheet items were categorized as: general information about the study designs, participants, and intervention, baseline information about certain parameters in the study as: Age, sex, heart rate, and systolic blood pressure, enzymes as malondialdehyde (MDA) and total antioxidant capacity (TAC), cardiac enzymes as creatine kinase MB (CKMB), and the outcome information including mortality rate, and the need for mechanical ventilation and hospitalization time

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The process splits NAD+ into nicotinamide (NAM) and O-acetyl-ADP-ribose