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No regulatory approvals exist for this indication

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis

Research shows that at least 10% of people over 60 have B12 deficiency, and many younger adults are also affected due to dietary choices or absorption problems

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Individual Variation Genetic polymorphisms in the beta-3 adrenergic receptor (ADRB3) affect how strongly individuals respond to beta-3 pathway stimulation