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In surgical settings, zinc infusions administered pre- and post-operatively in vascular surgery patients prevented the typical postoperative drop in serum zinc levels, resulting in a reduction in wound healing complications compared to the placebo group [550]

UA efficiently suppressed 27-HC-driven estrogen receptor activation by downregulating estrogen-responsive genes and estrogen response element activity

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This is particularly important for those with increased iron requirements, i.e

This action blocks the GPX4-GSH defense pathway, thus promoting ferroptosis [88]