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Use In Specific Populations Description: Omeprazole Injection is generally considered safe for use in pregnant and lactating women, although caution should be exercised, especially during the first trimester of pregnancy

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the inventors also surprisingly found inhibitory activity with certain embodiments of the invention where R 1 is methyl with dual positional substitutions (see e.g., compounds 2j, 2m, 2k, and 2l, Table 2)

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