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[DOI] [PubMed] [Google Scholar] 34.Zhang H., Go Y.M., Jones D.P

For example, certain bacteria can metabolize dietary nitrates into carcinogenic N-nitrosamines, which can damage DNA and initiate tumor development

CBD can directly influence various cell types, including neurons and immune cells, by targeting distinct molecular pathways, thereby modulating their functions

Mechanistically, -KG decreases Treg differentiation by inhibiting FOXP3 and upregulating inflammatory cytokines such as IFN-, Tbet, and Rorc, suggesting that Th1-type effector T cells are more dependent on glutaminolysis than Treg cells 136

Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease