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The most frequent causes are as follows: Common Causes of Hair Loss family history age alopecia areata cancer treatment childbirth illness trauma/stressors hormonal imbalance (such as thyroid) vitamin A toxicity nutritional deficiencies mast cell activation syndrome Identifying the root cause of hair loss is necessary in determining if regrowth is possible and in preventing permanent hair loss

of course, ascertainment is difficult if the characteristic clinical dyad of hemolytic anemia and metabolic acidosis is not recognized and urine organic acid studies are not obtained