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2024 Aug 26:462:141008

Zhang W, Borthakur G , Gao C, Chen Y, Lan YS, Ruvolo VR, Nomoto K, Zhao N, Konopleva M, Andreeff M

The hydrated form of cisplatin cross-links with nucleotides of nuclear and mitochondrial DNA to form adducts, inhibiting the indefinite replication of cancer cells 1,2

To achieve this objective, we examined various articles that collected the effects of non-essential heavy metals in the blood (plasma and serum) and urine samples from control individuals, smokers, and those with hypertension or different cardiovascular pathologies