glutathione peroxidase contains General reaction mechanisms for antioxidant File:Glutathione Reductase and Peroxidase Graphic.jpg

For inducers of cuproptosis, to raise intracellular Cu content, we collect some small molecule compounds targeting Cu ionophores: elesclomol, disulfiram, clioquinol, 8-quinolinol, schiff base, pyrithione, zinc metallochaperone, Cu(II)ATSM/Cu(II)GTSM, UM4118, they are capable of delivering Cu ions into cells

TIA1 mutations in amyotrophic lateral sclerosis and frontotemporal dementia promote phase separation and alter stress granule dynamics

Sci Rep 13 , 18448 (2023)

The abundance of proteins in the retina with increased intrinsically disordered regions of proteins (IRDs) that promote the propensity for phase separation emphasizes both a heightened reliance upon phase separation and the need to manage the potential pathological effects of protein aggregation from phase separation

Halbrook CJ, Lyssiotis CA, Pasca di Magliano M, Maitra A