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Global prevalence and epidemiological trends of Hashimotos thyroiditis in adults: A systematic review and meta-analysis

Of all, air humidity and temperature are two determinant factors to enhance the emergence of APF (99, 100)

Membrane-bound glutamine transporters (SLC1A5, SLC38A1/2, SLC6A14) mediate cellular uptake, then a mitochondrial variant of SLC1A5 delivers glutamine to the mitochondrial matrix, where glutaminase (GLS) converts it to glutamate