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This proteasomal inhibiting role can lead to a reduced proteasomal elimination of ubiquinated P-I (phosphorylated-inhibitor kappa), inhibiting nuclear translocation of NF-, suppressing NF-B activation and its consequences of tumor necrosis factor alpha (TNF-), and NO production (56) as well as, prophylactic atorvastatin suppresses NF-B activation in trigeminal nucleus caudalis (57)

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[Google Scholar] 21.Casterline JE, Allen LH, Ruel MT

Their main purpose is to provide a temporary physical framework for damaged tissues, facilitating cell attachment, migration, and proliferation through their porous structure, thereby offering the necessary physical support for the growth of new tissue (Janmohammadi et al., 2023