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In senescent cells, the transcription factor FOXO4 binds to p53 (the tumor suppressor "guardian of the genome"), sequestering p53 away from mitochondria where it would trigger apoptosis

A mechanism converting psychosocial stress into mononuclear cell activation

Additionally, it facilitates drought stress resistance by modulating stomatal aperture improves shelf life and storage quality of crop plants (Mekonnen et al

Statements Author contributions JW: Writing original draft

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