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Thus, its vasodilatory activity occurs through activation of the NO/cGMP pathway rather than blockage of KCa or KATP (Kang et al., 2005)

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*"Impact of pentadecapeptide BPC 157 on muscle healing impaired by systemic corticosteroid application."* Med Sci Monit

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This strategic layering is why sophisticated peptide combination protocols consistently outperform standard monotherapy in clinical practice