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PHL also has nephroprotective effects and is helpful in the treatment of hyperuricemia-related renal disorders since it simultaneously inhibits nucleotide-binding domain, leucine-richcontaining family, pyrin domaincontaining-3 (NLRP3) and uric acid reabsorption and attenuates uric acid-induced renal impairment 50

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Nirao Shah, MD, PhD, a professor of psychiatry, behavioral sciences and neurobiology at Stanford University School of Medicine

In clinical wound-care settings, adjunct topical GHK-Cu gels were associated with larger median reductions in ulcer area and fewer recorded wound infections relative to standard care alone, particularly in larger plantar lesions that were slower to progress under routine protocols