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Excess iron (including heme and non-heme iron) is mainly stored as ferritin and hemosiderin in the liver parenchyma and reticuloendothelial system, especially in the reticuloendothelial cells of the bone marrow, spleen, and liver, along with free ferrous ions, forming a dynamic iron pool cycle in the body

5HT temporal profiles significantly differed between the two groups, with the levels being consistently higher in the responders at baseline, week 4, and week 8, while the decline in HRSD 17 scores was significantly lower at both 4 and 8 weeks compared with baseline (Fig

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