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Lack of over-expression effects (Supplementary Fig

Editor information Editors and Affiliations Rights and permissions Copyright information 2022 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature About this chapter Cite this chapter Vuolo, M.M., da Silva-Maia, J.K., Batista, .G

Dulbeccos Modified Eagles Medium (DMEM), fetal bovine serum (FBS), 0.25% trypsin, and penicillin-streptomycin (100) were purchased from Gibco (Grand Island, USA)

Characterization of major phytocannabinoids, cannabidiol and cannabinol, as isoform-selective and potent inhibitors of human CYP1 enzymes

The results of ELISA and Western blot analysis showed that compared with cells without treatment, levels of IL-6 and TNF- and protein levels of Collagen I and -SMA elevated in cells treated with CSE, while levels of IL-6 and TNF- and protein levels of Collagen I and -SMA decreased in cells treated with CSE and PBS compared with cells treated with CSE plus NAC (Fig