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Description

While aflatoxins primarily cause immune suppression, the resulting immune imbalance can sometimes trigger autoimmune responses, where the immune system attacks the body's own tissues (Kraft et al

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By improving lipid breakdown and decreasing adipose inflammation, TFEB-induced GDF15 protects against diet-induced obesity and insulin resistance [90]

Indeed, in vitro studies showed that cells expressing the sst 5 TMD2 mainly respond to cortistatin, whereas those expressing sst 5 TMD4 were exclusively activated by somatostatin and those bearing the sst 5 TMD1 responded to both ligands (Cordoba-Chacon et al., 5 TMD4, while somatostatin activates the sst 5 TMD5 (Duran-Prado et al., Somatostatin in the brain exerts a wide variety of physiological functions besides the initially described inhibitory effect on growth hormone release