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As with the prior assessments, subjects were asked to report for testing in the morning following 12 hr without food and to not participate in heavy exercise during the 24 hr period before testing

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The presence or absence of pain is a clear indicator of which phase the patient is in

Considering the established involvement of the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway and transforming growth factor-beta1 (TGF-1) in RA, this research aimed to assess efficacy and safety of L-carnitine as an adjunct therapy targeting these pathways