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[PubMed: 6075449] 10

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Furthermore, a study revealed that liver-specific Zip8 KO mice exhibited significant decreases in systemic Mn levels under both Mn-rich and Mn-depleted conditions, indicating that hepatic ZIP8 mediates Mn reabsorption from bile to help maintain systemic homeostasis (Powers et al., 2023)

INGREDIENTS: WATER (AQUA, EAU), SODIUM LAURETH SULFATE, COCAMIDOPROPYL BETAINE, SODIUM CHLORIDE, FRAGRANCE (PARFUM), AMYRIS BALSAMIFERA BARK OIL (SANDALWOOD), PEG-4 RAPESEEDAMIDE, POLYQUATERNIUM-7, GLYCERIN, HYDROXYPROPYL METHYLCELLULOSE, SODIUM PEG-7 OLIVE OIL CARBOXYLATE, METHYLCHLOROISOTHIAZOLINONE, METHYLISOTHIAZOLINONE, TETRASODIUM EDTA, CITRIC ACID, BUTYROSPERMUM PARKII (SHEA) BUTTER, PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL, MAGNESIUM SULFATE (EPSOM SALT), ALOE BARBADENSIS LEAF JUICE (DECOLORIZED), SODIUM HYDROXIDE, PEG/PPG-18/18 DIMETHICONE Thank you

The solutions with different pH values proved that the efficacy of PTL is not dependent on the lower pH, since the pH solutions comparable to the pH of PTLs did not exhibit any inhibition efficacy