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We're going to break this down from a practical, lab-focused perspective

Once in circulation, thiamine is transported to cells throughout the body, where it is converted into its active form, thiamine pyrophosphate (TPP)

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

However, this marker is not completely clear because HMNT is only responsible for about 70% of histamine degradation the rest is done by the enzyme DAO