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Participants with the highest intake of heme iron, a well-absorbed, protein-bound form of iron found in meat and seafood, had a 21% higher risk of symptomatic gallstones compared with those with the lowest intake, but there was no significant link between the intake of non-heme iron, which is found predominantly in plant-based foods, and symptomatic gallstones (Tsai 2007)

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From there, the active ingredients get absorbed rapidly into the bloodstream