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Current models do not fully explain the mechanisms underlying resistance to therapy ( + MM cells within hours to days after the first infusion ( Figure 6 ), underscore the need to further investigation into the CD38/ADA/purinergic axis to optimize anti-CD38 strategies in MM

A 2013 study linked low vitamin B12 and folate levels with an increased risk of age-related macular degeneration ( Although the reduction in risk cant be attributed to vitamin B12 only, it does suggest that getting enough may be important

Recommendations for examining and interpreting funnel plot asymmetry in metaanalyses of randomised controlled trials

It needs to be reconstituted prior to use

B12 injections can help lower homocysteine levels, reducing the risk of developing cardiovascular issues