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These limitations highlight a need for systematic and standardized research to reliably assess and translate pharmacological interventions from ASD animal models to human clinical relevance

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In reactions pretreated with the inhibitors, 10 mM EDTA (Sigma #5134), 100 M DTPA (Sigma #D6518), 2 mM PAG (Sigma #P7888), or 2 mM AOAA (Sigma #C13408) were added to the reaction mixture prior to the addition of the chemical or tissue catalyst