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Lieberman HR, Wurtman RJ, Emde GG, Roberts C, Coviella IL

ACS Nano 14 (5), 53605370

Meng F, Xu R, Wang S, Xu Z, Zhang C, Li Y, et al

Most users notice visible results in 48 weeks with consistent use

Under physiological conditions, it supports synaptic plasticity [346], whereas under pathological states, such as during astrocytic necroptosis, proBDNF may exert neurotoxic effects and promote apoptotic signaling [349]