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A recent study showed polyethylene glycol-poly (lactic-co-glycolic acid) (PEGPLGA) nanoencapsulation of EGCG was shown to reduce epidermal thickness from 109.4 m to 43.6 m after 21 days of topical application, accompanied by decreases in lactate dehydrogenase and MDA, and increases SOD, GSH, and T-AOC by 35%60%

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Lo HJ, Khler JR, Didomenico B, Loebenberg D, Cacciapuoti A, Fink GR