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Scaldaferri F, Riccardo L, Petito V, Cufino V, Bilotta M, Arena V, et al

Moreover, local application of the GABAA receptor modulator midazolam to the cochlea reversed salicylate-induced increases in cochlear BDNF expression while concurrently reducing tinnitus perception in the animal model, accompanied by restoration of cortical Arg3.1 expression, revealing a functional BDNF-mediated cochlearcortical axis in tinnitus pathophysiology (Panford-Walsh et al., 2008)