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147 DHODH, which is located in the inner mitochondrial membrane, is a critical enzyme responsible for catalyzing the de novo synthesis pathway of pyrimidine nucleotides

To further investigate the intracellular dynamics of MLKL molecules in response to acrolein, we performed immunofluorescence staining and saw that TSZ, but not acrolein, induced localization of MLKL to the plasma membrane (Fig