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GH secretion is regulated by a complex feedback system involving the pituitary gland, hypothalamus, and other organs, and predominantly occurs during deep sleep

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It is an option for participants with vitamin D levels that are known to be much lower than desired, or for those who are needing to raise levels quickly due to a health condition or health concern (such as boosting the immune system)

Clinical observations suggest that earlier intervention, ideally beginning during the active weight loss phase, may optimize outcomes by supporting ongoing tissue adaptation rather than attempting to reverse established structural changes