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NM-MRI signal loss in PD has been consistently demonstrated in the SN and LC 42,43,44,45

Biorg Med Chem 25:61806189 Bekaii-Saab T, Wesolowski R, Ahn DH, Wu C, Mortazavi A, Lustberg M, Ramaswamy B, Fowler J, Wei L et al (2019) Phase I immunotherapy trial with two chimeric HER-2 B-cell peptide vaccines emulsified in montanide ISA 720VG and nor-MDP adjuvant in patients with advanced solid tumors phase I immunotherapy trial with two B-cell vaccines

Over 55 million individuals worldwide have dementia, with more than 60% living in low- and middle-income countries