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More recently a number of genome-wide studies, using chromatin immunoprecipitation (ChIP), have increased our knowledge of androgen-regulated genes and have demonstrated a significant variability in DNA response element architecture, with imperfect palindromic sequences and half-sites identified as potential receptor binding sites (30, 127-131)

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Each receptor is tied to a different downstream pathway, which is why one compound can influence pigmentation, sexual behaviour and appetite in study models

277 Therefore, provision of L-carnitine might help to restore muscle mass and function