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I think you need to give the cortisone a little bit more time to work

doi: 10.1016/j.ejpb.2011.10.015 226

Dehydroabietic acid isolated from Pinus elliottii exerts in vitro antileishmanial action by pro-oxidant effect, inducing ROS production in promastigote and downregulating Nrf2/ferritin expression in amastigote forms of Leishmania amazonensis