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An increase in BUN within the first 24 h is now recognized as a significant risk factor for mortality and is closely associated with multiple organ failure and severe disease progression

Front Neurosci 19:1632905, 2025

Other causes Other causes of acute liver failure include ischemic hepatitis, autoimmune hepatitis, Wilson disease, Budd-Chiari syndrome, and HELLP (hemolysis, elevated liver enzymes and low platelets) syndrome

Silencing USF1 can block this pathway, thus reducing EndMT and atherosclerosis development in vitro and in vivo [95]

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