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Interestingly, the gut metabolic module aspartate degradation I, which converts L-aspartate to oxaloacetate by aspartate aminotransferase, was elevated in SAD patients and the authors hypothesized that bacterial aspartate aminotransferase enzyme activity may represent a link between gut microbiome function and the tryptophan-kynurenine pathway, a key physiological system in psychiatric disorders (Butler et al., 2023)

The supernatant was used for ELISA analysis of IgA (Invitrogen) and albumin (Bethyl Laboratories, Montgomery, TX) levels according to the manufacturers instructions

The cells were rinsed and incubated with mytomycin C (5 g ml 1 ) for 1 h to inhibit the cancer cell proliferation

L-Carnitine This product has been discontinued and is no longer available for purchase

IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation