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The practical solution: use a smaller reconstitution volume (1.0 mL) during the early titration phase so the total solution volume is smaller and you draw more per dose (relatively), or accept that you will waste some peptide during the titration stages

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The overall backbone RMSD value was monitored for 21 active site residues throughout the entire trajectory (Supplementary Figure S12)

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doi: 10.1016/0196-9781(87)90129-X

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