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ASDs, encompassing full-syndrome autism (autistic disorder), Asperger syndrome, tuberous sclerosis, Angel man syndrome, congenital rubella, Down syndrome, Rett syndrome, asphyxia, childhood disintegrative disorder, and pervasive developmental disorder not otherwise specified (PDDNOS), are now grouped as ASDs, also known as pervasive developmental disorders (PDDs)

A correlation between male infertility and a GPX4 defect has actually been reported [17, 18]

The concentration of double-stranded (ds) DNA present in the DNA stock solution was quantified using a fluorescent dye assay (Qubit, Invitrogen)

Cells were washed and resuspended in FACS buffer and analyzed on an LSR Fortessa (BD Biosciences) operated on BD FACSDiva software (v9.0)